Work-Up of Secondary Causes
What is the work-up for secondary causes of osteoporosis?
All patients diagnosed with osteoporosis should be considered candidates for evaluation for secondary (treatable) causes, with some or all of these tests:
Serum calcium and albumin to evaluate for hyperparathyroidism
TSH to evaluate for hyperthyroidism
Basic metabolic profile (BMP) to evaluate for renal failure and acidosis
Alkaline phosphatase to evaluate for other bony abnormality (Paget's, multiple myeloma)
Possibly 25-OH vitamin D level to evaluate for deficiency
Testosterone level in men with treatable symptoms (testosterone, like estrogen is not recommended as therapy for osteoporosis, except when the benefit outweighs the risk)