Risks of Medical Therapies

Previous | Next

Both short-and long-term anti-secretory therapy with proton pump inhibitors (PPIs) has linked to the following:

• Small intestinal bacterial overgrowth

• Vitamin B12, C, iron, malabsorption

• Increased risk of community-acquired pneumonia

• Increased risk of osteoporotic fracture, predominantly hip fracture, secondary to impaired osteoblast activity and decreased calcium absorption

• Increased risk of Clostridium difficile, Salmonella, and Campylobacter-associated diarrhea

• Inhibition of anti-platelet agents, e.g., clopidogrel

• Decreased protein absorption

Previous | Next