Side Effects
Become informed about evidence, dosage, safety and side effects of SAMe.
Now that you have learned about SAMe, go to the next section to learn more about 5-HTP.
Side effects are generally few, but like other antidepressants, SAMe can cause:
Agitation
Gastrointestinal (GI) upset
Headache
Emotional numbing
Enteric coated capsules can minimize the GI effects as SAMe is mostly absorbed in the intestines.