Vitamin D
In this section, we will discuss the effect that nutrition can have on mood. Click on the links below to learn more.
Now that you have learned about nutrition and its effects on depression, move on to the next section to learn about which herbs and supplements can be effective.
It has been postulated that vitamin D may play a role in treating depression given the extent to which it is influenced by exposure to sunlight and recognizing the positive relationship shown between phototherapy and Seasonal Affective Disorder. Epidemiological studies reveal that low levels of vitamin D may be associated with depression. In one small study, a one time administration of 100,000 international units of vitamin D2 was significantly more effective than phototherapy at improving symptoms of seasonal affective disorder (Gloth), although randomly supplementing elderly women did not show an effect in another, larger trial (Dumville).
Given the existing evidence, it makes sense to check a 25-OH vitamin D level in all patients with depression but especially those affected by Seasonal Affective Disorder.
Anyone with levels less than 35 probably deserves supplementation with 1000-2000 IU of vitamin D3 (the active form) per day or even 5000 IU per day for patients who are very low (less than 15) or for those who do not bump appropriately on 2000 IU per day.
Too much vitamin D can lead to symptoms of hypercalcemia, constipation, irritability, weakness, and anorexia. Toxicity is excedingly rare, especially among individuals with low blood levels. Levels can be checked every one to three months for patients who have concerns.
To access additional information about vitamin D, see the Natural Standard Database.