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ESC AF guideline 2024Principes van anti-arritmica
Treatment is aimed at reducing AF-related symptoms;
Efficacy of antiarrhythmic drugs to maintain sinus rhythm is modest;
Clinically successful antiarrhythmic drug therapy may reduce rather than eliminate the recurrence of AF;
If one antiarrhythmic drug ‘fails’, a clinically acceptable response may be achieved with another agent;
Drug-induced pro-arrhythmia or extracardiac side-effects are frequent;
Safety rather than efficacy considerations should primarily guide the choice of antiarrhythmic drug.