EFFECTS OF N-(5-bromo-1H-indole-3-yl)methylene nicotinohydrazide ON THIOACETAMIDE-INDUCED LIVER CIRRHOSIS IN RATS
Mahmood Ameen Abdulla
mahmood.ameen@cihanuniversity.edu.iq
Abstract- Hepatoprotecting effects of this compound was evaluated against thioacetamide (TAA)-induced liver cirrhosis in rats. Thirty adult SD rats were randomly separated into five groups of six rats each. TAA-control group showed significant rise in serum liver biochemical markers go together with by a considerable decrease in the level of total protein and albumin in comparison to normal control group. Hepatotoxic group showed decreased CAT and SOD activity and increase MDA.
Keywords- liver cirrhosis, TAA
Date: 23/04/2020
Place: Online