Virulence factors gene polymorphism in Toxoplasma gondii
Dr. Hadi Mahdi Ahmad Alsakee
hadi.alsakee@cihanuniversity.edu.iq
Abstract- Toxoplasmosis is a worldwide infectious disease caused by the obligate intracellular protozoan parasite, Toxoplasma gondii. Roughly, it affects about one third of the world’s population and humans may result in congenital, ocular, or encephalic toxoplasmosis. Congenital toxoplasmosis has been associated with abortion and still- birth, as well as neonatal mortality and morbidity. This parasite show highly clonal variation and more than 95% of the strains that have been isolated from North America and Europe grouped into one of three lineages, types I, II and III. Even though strains show approximately 98% genetic homology, they display dramatic differences in virulence. This seminar discuss the genetic basis of some Toxoplasma gondii virulence factors and their role in the morbidity.
Keywords- genetic homologyToxoplasma gondiivirulence
Date: 4/12/2018
Place: Department of Biology