- Routine induction dose : 0.3 mg/kg
- Onset time : rapid (one arm–brain circulation)
- adrenocortico suppressive effect로 인하여 corticosteroid 합성을 방해할 수 있으므로, sedation은 매우 짧은 용도 외에는 잘 쓰이지 않음. 같은 이유로 continuous infusion은 금기.
Other uses
- Treatment in Hypercortisolemia
Side effects
- nausea, vomiting (associated with PONV)
- pain on injection ( Pain on injection may be reduced by injecting IV lidocaine, 20 to 40 mg immediately before injection of etomidate.)
- myoclonic movement (reduced by premedication with a hypnotic agent such as midazolam or a small dose of magnesium 60 to 90 seconds before the induction dose of etomidate is given.)
- hiccups
Reference
Miller’s Anesthesia, 8th edition, Ch. 30, P. 850
Morgan and Mikhail's Clinical Anesthesiology, 5th edition, Ch.9, P.184