Keyword
Diltiazem
Pharmacologic class: Calcium channel blocker
Indication
- Angina pectoris and vasospastic (Prinzmetal's) angina
- hypertension
- supraventricular tachyarrhythmias
- atrial flutter or fibrillation
Dosages ( IV ) : When giving I.V., dilute in dextrose 5% in water or normal saline solution
- 0.25 mg/kg by I.V. bolus over 2 minutes
- 15분 뒤에도 반응이 없으면 I.V. 0.35 mg/kg over 2 minutes
- Infusion : I.V. infusion at 10 mg/hour (at a range of 5 to 15 mg/hour) for up to 24 hours.
- onset : 2-5 min , peak : 2-4 hr , duration : unknown
Further readings
https://www.cjp.co.kr/upload_file/product/product_img/%ED%97%A4%EB%A5%B4%EB%B2%A4%EC%A3%BC50mg%20%EC%84%A4%EB%AA%85%EC%84%9C.pdf
Reference
Miller’s Anestheisa, 8th edition, Ch. 108 P.3197
https://www.cjp.co.kr/upload_file/product/product_img/%ED%97%A4%EB%A5%B4%EB%B2%A4%EC%A3%BC50mg%20%EC%84%A4%EB%AA%85%EC%84%9C.pdf