Rocuronium

Keyword

Rocuronium

Action

• intubating dose : 0.45-0.9 mg/kg
• onset for intubation : 1.5 min
• duration : 35-75 min
• maintenance dose : 0.15mg/kg
• infusion rate : 9-12 mcg/kg/min
• rapid-sequence induction dose : 0.9-1.2mg/kg (onset of action : 60-90 sec)

Characteristic

• eliminated primarily by the liver
• prolonged by hepatic failure and pregnancy
• no active metabolites ; better choice in requiring prolonged infusions in the ICU setting.
• elderly patients ; prolonged duration of action due to decreased liver mass.

Reference