Dopamine

Keyword

Dopamine

Mechanism

• Low dose (0.5-3mcg/kg/min) : primarily activates dopaminergic Rc ; vasodilates the real vasculature, promote diuresis, natriuresis
• Moderate dose (3-10mcg/kg/min) : B1-stimulation ; increase myocardial contractility, HR, systolic BP, C.O
• High dose (10-20mcg/kg/min) : a1-effect ; increase peripheral vascular resistance, decrease renal blood flow

Dose

Continuous infusion : 1-20mcg/kg/min

(1 vial : 200 or 400 mg, 5-10mL)

Effect

• improve cardiac output
• support blood pressure
• maintain renal function

Reference