Thunbergia grandiflora originates from India, parts of China, and South Asia, but is widely cultivated and naturalized in tropical and subtropical areas. Currently, the plant can be found in Mexico, Central America, the West Indies, South America, tropical Africa, Southeast Asia, Australia, and the Pacific Islands. Thunbergia grandiflora is an important economic species widely cultivated as an ornamental plant and a hedge plant in tropical and subtropical regions, although in some countries, including Australia, it is classified as a "dangerous weed." In tropical Africa (Tanzania and Uganda), the plant has been used as a source of green fertilizer and firewood. Furthermore, Thunbergia grandiflora also has health benefits and has been used as a medicinal plant in traditional treatments in Asia and Africa. In addition, its leaves can be cooked as a vegetable.

Thunbergia grandiflora can typically be found growing on forest edges, roadsides, riverbanks, open forests, and plantations in tropical and subtropical regions, at altitudes of 200–1,300 m above sea level (m.a.s.l.). Its growth requires a position in full sun and it is not tolerant of shaded conditions, with an average annual rainfall ranging between 500–3,500 mm. This plant prefers fertile, moist, but well-drained soil.

• Root (Akar) Has a tuberous root with a deep taproot, the root continually produces suckers/shoots.

• Stem (Batang) Cylindrical, four-angled, striated, pubescent (hairy). The stem cross-section has a hollow pith. Young stems are green, while older stems are quite thick, turn brown, and become somewhat round in shape.

• Leaves (Daun) Opposite arrangement. The shape of the leaf blade varies, from ovate to triangular-ovate. The leaf tip is acute to acuminate (runcing hingga meruncing), the base is cordate (heart-shaped), and the margin is sharply toothed (bergigi tajam). The upper surface is dark green, glossy, pubescent, with slightly prominent venation. The lower surface is light green, dull, glabrous or pubescent, with prominent venation.

• Flower (Bunga) Large, trumpet-shaped, solitary, or in pairs in the leaf axils, or arranged in terminal, drooping racemes with 2–4 flowers per node. The calyx is green, ring-shaped. The corolla is purplish-blue or white, with 5 lobes. The tube is 6–7 cm long, pale yellow on the inside, narrowing at the base.

• Fruit (Buah) Capsule shaped, pubescent (hairy), subglobose (nearly spherical) at the base, the upper part is beak-shaped, and splits into two parts.

• Seed (Biji) Small, oval, flat, covered with brown scales.

• Propagation is done generatively (seeds) and vegetatively (stem cuttings, stolons/runners).

Treats snake bites, swelling due to falls or fractures, dysentery, cataracts, diabetes, gout, malaria, marasmus (severe energy and protein deficiency), ophthalmia (eye inflammation), postpartum preeclampsia, rheumatism, elephantiasis (kaki gajah), heart disease, stomach complaints, menorrhagia (excessive menstruation), ear infections, and is used to treat drug and alcohol abuse. It also has antipyretic (fever-reducing), anthelmintic (deworming), antioxidant, and anti-inflammatory activities.

Alkaloids, phenols, iridoid glycosides, isounedoside, grandifloric acid, and essential oils (α-3-octanol, 3,7 dimethyl 1,6-octadien-3-ol, 2-methoxy-3-(2-propenyl) phenol, methyl salicylate, isopropyl hexadecanoate).