This plant is presumed to have originated in the Middle East since ancient times. One country that continues to develop E. milii to this day is Thailand. Besides Thailand, Indonesia and Malaysia have also begun to cultivate E. milii. In Indonesia, this euphorbia is known by the name Pakis Giwang.

E. milii prefers a dry microclimate (Rh 70%) and requires a planting medium that is more moist compared to other euphorbia types. In low humidity, the plant canopy can grow well when accompanied by adequate watering. Meanwhile, excessively high air humidity will reduce the plant's metabolic activity, making it susceptible to disease attacks. However, E. milii can still be grown in the highlands provided the lighting is sufficient and the rainfall is low.

• Root: Euphorbia plants have a taproot type.

• Stem: Divided into two variations: one stem shape is round, while the other is somewhat angular. Although some euphorbia species have curved stems, most are upright and towering.

• Leaves: E. milii leaves are oval with sizes varying according to the hybrid and cultivar.

• Flowers: The flowers are small and yellow with colorful cyathia (bracts) as a result of hybridization. Generally, this plant has a perfect true flower with complete male and female sexual organs.

• Fruit: The euphorbia fruit looks unique, as it is shaped like a capsule composed of several clusters, totaling 3–4 fruits.

• Seed: The ornamental euphorbia plant has seeds characterized by a dark brown color and a perfectly round shape. Its diameter is not too large and is of the anatar type, measuring only 0.3–0.5 cm.

• Propagation is done generatively (by seed) and vegetatively (by cuttings).

Euphorbia can cure various diseases such as ringworm, boils, inflammation of the inner ear (radang anak telinga), and constipation.

The groups of secondary metabolite compounds are alkaloids, flavonoids, saponins, tannins, steroids, and triterpenoids.