Primary cutaneous T-cell lymphomas

WHO 2022 Primary cutaneous T-cell lymphoid proliferations and lymphomas (CTCL)

Primary cutaneous T-cell lymphoid proliferations and lymphomas (CTCL) comprise a dedicated family within the mature T/NK-cell neoplasms chapter in WHO-HAEM5, and include nine entities;

• • • Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder

    • Primary cutaneous acral CD8-positive lymphoproliferative disorder

    • Mycosis fungoides

    • Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis

    • Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma

    • Subcutaneous panniculitis-like T-cell lymphoma

    • Primary cutaneous gamma/delta T-cell lymphoma

    • Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma

    • Primary cutaneous peripheral T-cell lymphoma, NOS