Tumour-like lesions with B-cell predominance
New addition to WHO-HAEM5: Tumour-like lesions with B-cell predominance.
For the first time, the WHO ‘Blue Book’ on haematolymphoid tumours introduces tumour-like lesions, including five entities in a distinct class of tumour-like lesions with B-cell predominance.
unicentric Castleman disease
idiopathic multicentric Castleman disease
IgG4-related disease
non-neoplastic B-cell predominant lymphoid proliferations involving lymph nodes and/or extranodal sites that can mimic lymphomas, including progressive transformation of germinal centers, infectious mononucleosis, florid reactive lymphoid hyperplasia/lymphoma-like lesion of the female genital tract, and systemic lupus erythematosus.
