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TYK2
Name
Name
Tyrosine kinase 2
Relevant Pathway
Relevant Pathway
Function
Function
Member of JAK family, acts through downstream STAT proteins to control biological events
Critical role in immune cell function and host defenses
Role in Longevity
Role in Longevity
JAK pathway inhibition suppresses SASP in senescent cells and alleviates age-related tissue dysfunction
Reference
Reference
Xu (2016), Rawlings (2004)
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