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Applanatumol I
Chemical Formula: C16H16O8
Chemical Formula: C16H16O8
Exact Mass: 336.08 g/mol
Exact Mass: 336.08 g/mol
Molecular Weight: 336.29 g/mol
Molecular Weight: 336.29 g/mol
Elemental Analysis: C(57.14%) H(4.80%) O(38.06%)
Elemental Analysis: C(57.14%) H(4.80%) O(38.06%)
SMILES: C1C[C@]2(C(=O)OC[C@]2([C@H]1O)C(=O)O)CC(=O)C3=C(C=CC(=C3)O)O
SMILES: C1C[C@]2(C(=O)OC[C@]2([C@H]1O)C(=O)O)CC(=O)C3=C(C=CC(=C3)O)O
PubChem CID: 132542818
Chemical Structure:
Alternative Names
Alternative Names
N/A
Source
Source
Ganoderma sinense (TCM)
Protein Target/Signalling
Protein Target/Signalling
PI3K/Akt
Nrf2/HO-1
Biological Pathway
Biological Pathway
mTOR
IGF/IIS
Telomeres
Antioxidant signalling
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Biological Activity
Biological Activity
Protection of human normal liver cells against H2O2-induced cell damage and apoptosis, antioxidant effects via PI3K/Akt-mediated activation of Nrf2/HO-1 pathway, protection of cardiomyocytes from IR injury
Reference
Reference
Gao (2018b)
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