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Nordihydroguaiaretic acid
Chemical Formula: C18H22O4
Chemical Formula: C18H22O4
Exact Mass: 302.15 g/mol
Exact Mass: 302.15 g/mol
Molecular Weight: 302.4 g/mol
Molecular Weight: 302.4 g/mol
Elemental Analysis: C(71.50%) H(7.33%) O(21.17%)
Elemental Analysis: C(71.50%) H(7.33%) O(21.17%)
SMILES: CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
SMILES: CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
PubChem CID: 4534
Chemical Structure:
Alternative Names
Alternative Names
NDGA
Masoprocol
Source
Source
Larrea divaricata
Protein Target/Signalling
Protein Target/Signalling
P300
Biological Pathway
Biological Pathway
Epigenetic modification
Autophagy
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in mice
Biological Activity
Biological Activity
Increase in lifespan of genetically heterogenous male mice, but not females; inhibitor of p300 and induces autophagy
Reference
Reference
Strong (2008), Tezil (2019)
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