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Aspirin
Chemical Formula: C9H8O4
Chemical Formula: C9H8O4
Exact Mass: 180.04 g/mol
Exact Mass: 180.04 g/mol
Molecular Weight: 180.16 g/mol
Molecular Weight: 180.16 g/mol
Elemental Analysis: C(60.00%) H(4.48%) O(35.52%)
Elemental Analysis: C(60.00%) H(4.48%) O(35.52%)
SMILES: CC(=O)OC1=CC=CC=C1C(=O)O
SMILES: CC(=O)OC1=CC=CC=C1C(=O)O
PubChem CID: 2244
Chemical Structure:
Alternative Names
Alternative Names
N/A
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
COX-1
COX-2
EP300
Biological Pathway
Biological Pathway
Inflammation
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in male mice
Caloric restriction mimetic
Anti-inflammatory
Biological Activity
Biological Activity
Increase in lifespan of genetically heterogenous male mice, but not females
Identified as a caloric restriction mimetic due to its ability to induce autophagy by inhibiting EP300 in C. elegans
Reference
Reference
Strong (2008), Pietrocola (2018)
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