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Butein
Chemical Formula: C15H12O5
Chemical Formula: C15H12O5
Exact Mass: 272.07 g/mol
Exact Mass: 272.07 g/mol
Molecular Weight: 272.25 g/mol
Molecular Weight: 272.25 g/mol
Elemental Analysis: C(66.17%) H(4.44%) O(29.38%)
Elemental Analysis: C(66.17%) H(4.44%) O(29.38%)
SMILES: C1=CC(=C(C=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O)O
SMILES: C1=CC(=C(C=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O)O
PubChem CID: 5281222
Chemical Structure:
Alternative Names
Alternative Names
3,4,2′,4′-tetrahydroxychalcone
Source
Source
Toxicodendron vernicifluum (TCM), plants
Protein Target/Signalling
Protein Target/Signalling
SIRT1
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in Saccharomyces cerevisiae
SIRT1 activation
Biological Activity
Biological Activity
Attenuation of sepsis-induced brain injury in mice
Chalcone derivative, sirtuin activating compound
Reference
Reference
Zhu (2019), Howitz (2003)
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