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(-)-Epicatechin
Chemical Formula: C15H14O6
Chemical Formula: C15H14O6
Exact Mass: 290.08 g/mol
Exact Mass: 290.08 g/mol
Molecular Weight: 290.27 g/mol
Molecular Weight: 290.27 g/mol
Elemental Analysis: C(62.07%) H(4.86%) O(33.07%)
Elemental Analysis: C(62.07%) H(4.86%) O(33.07%)
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
PubChem CID: 72276
Chemical Structure:
Alternative Names
Alternative Names
N/A
Source
Source
Cocoa
Tea
Protein Target/Signalling
Protein Target/Signalling
SP1
SIRT1
Biological Pathway
Biological Pathway
Sirt
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Increased survival
Reduce in age-related decline in mice
Biological Activity
Biological Activity
Cardioprotective: Suppression of Angiotensin II-induced cardiac hypertrophy via SP1/SIRT1 activation, prevention of blood pressure increase
Increase in survival, attenuation of ageing-related deterioration of skeletal muscles, protection against ageing-related decline in niconate and nicotinamide metabolism in ageing mice
Reference
Reference
Dong (2017), Kluknavsky (2016), Schroeter (2006), Loke (2008), Si (2019)
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