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Tenovin-1
Chemical Formula: C20H23N3O2S
Chemical Formula: C20H23N3O2S
Exact Mass: 369.15 g/mol
Exact Mass: 369.15 g/mol
Molecular Weight: 369.5 g/mol
Molecular Weight: 369.5 g/mol
Elemental Analysis: C(65.01%) H(6.27%) N(11.37%) O(8.66%) S(8.68%)
Elemental Analysis: C(65.01%) H(6.27%) N(11.37%) O(8.66%) S(8.68%)
SMILES: CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C
SMILES: CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C
PubChem CID: 1013376
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
SIRT1
SIRT2
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Biological Activity
Biological Activity
Inhibition of both SIRT1 and SIRT2 in vitro, activation of p53 and inhibition of tumour growth in vivo
Reference
Reference
Lain (2008), Villalba (2012)
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