• Sterol regulatory element-binding protein 1 

• Lipid metabolism

• mTOR

• Lipid homeostasis, three forms: SREBP-1a, SREBP-1c and SREBP-2. SREBP-1 regulates fatty acid synthesis to a greater extent than cholesterol synthesis, while SREBP-2 selectively transcriptionally activates genes in cholesterol biosynthesis

• Modulates cell senescence: activation mediates lipid biosynthesis directly involved in senescence-associated organelle biogenesis

Eberlé (2004), Kim (2010)