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MOAG-4
Name
Name
Modifier of aggregation 4
Relevant Pathway
Relevant Pathway
Function
Function
Homologous to SERF1A and SERF2 in humans
Regulator of age-related proteotoxicity, acts through alternative pathway distinct from molecular chaperones and proteases in worms
Role in Longevity
Role in Longevity
Promotes aggregation of aggregation-prone disease proteins, inactivation of MOAG-4 suppresses age-related proteotoxicity
Reference
Reference
López-Otín (2013), van Ham (2010)
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