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STAT
Name
Name
Signal transducer and activator of transcription proteins
Relevant Pathway
Relevant Pathway
Function
Function
Latent transcription factors residing in cytoplasm until activated
Role in Longevity
Role in Longevity
JAK pathway inhibition suppresses SASP in senescent cells and alleviates age-related tissue dysfunction
Diminished JAK/STAT signalling causes early onset ageing defects in stem cell cytokinesis in germline stem cells in the Drosophila testis
Reference
Reference
Xu (2016), Rawlings (2004), Lenhart (2019)
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