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SRT1720
Chemical Formula: C25H23N7OS
Chemical Formula: C25H23N7OS
Exact Mass: 469.17 g/mol
Exact Mass: 469.17 g/mol
Molecular Weight: 469.6 g/mol
Molecular Weight: 469.6 g/mol
Elemental Analysis: C(63.95%) H(4.94%) N(20.88%) O(3.41%) S(6.83%)
Elemental Analysis: C(63.95%) H(4.94%) N(20.88%) O(3.41%) S(6.83%)
SMILES: C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5
SMILES: C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5
PubChem CID: 24180125
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
SIRT1
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in mice
Activator of Sirt1, disputed
Biological Activity
Biological Activity
Lifespan extension, delayed onset of age-related metabolic diseases, and improved general health in mice fed a standard diet after SRT1720 supplementation. Allosteric binding to SIRT1
Reference
Reference
Mitchell (2014), Dai (2010), Pacholec (2010)
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