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Ras
Name
Name
Rat sarcoma virus
Relevant Pathway
Relevant Pathway
Function
Function
Family of small GTPases, key proteins in signalling network of cellular processes i.e. proliferation, differentiation, apoptosis, senesence, and metabolism. Hyperactivation is highly oncogenic
Role in Longevity
Role in Longevity
Inhibition of Ras extends lifespan downstream of reduced IIS signalling
Reference
Reference
Slack (2015)
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