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Pterostilbene
Chemical Formula: C16H16O3
Chemical Formula: C16H16O3
Exact Mass: 256.11 g/mol
Exact Mass: 256.11 g/mol
Molecular Weight: 256.30 g/mol
Molecular Weight: 256.30 g/mol
Elemental Analysis: C(74.98%) H(6.29%) O(18.73%)
Elemental Analysis: C(74.98%) H(6.29%) O(18.73%)
SMILES: COC1=CC(=CC(=C1)/C=C/C2=CC=C(C=C2)O)OC
SMILES: COC1=CC(=CC(=C1)/C=C/C2=CC=C(C=C2)O)OC
PubChem CID: 5281727
Chemical Structure:
Alternative Names
Alternative Names
Trans-3,5-dimethoxy-4-hydroxystilbene
Source
Source
Blueberries
Pterocarpus marsupium
Dracaena cochinchinensis
Grapes
Plums
Blackberries
Protein Target/Signalling
Protein Target/Signalling
SIRT1
BDNF/ERK/CREB
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Reduces production of ROS. Modulates LOX-1, NF-κB, SOD, iNOS, COX-2 and more
Biological Activity
Biological Activity
Structurally similar to resveratrol, but with increased bioavailability
Restoration of SIRT1 function for attenuation of IR injury in cardiomyocytes
Alleviation of renal fibrosis in hyperuricemic nephropathy in mice
Neuroprotective in rats via BDNF/ERK/CREB-associated signalling pathways
Redox homeostasis modulation in cardiac myoblasts and heart tissue
Reference
Reference
McCormack (2013), Li (2018a), Guo (2016), Pan (2019), Yang (2019), Couto (2018)
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