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ATG
Name
Name
Autophagy-related proteins
Relevant Pathway
Relevant Pathway
Function
Function
Family of proteins (ATG1-35) first identified in yeast. ATG protein 1-10 essential for autophagosome formation in macroautophagy
Role in Longevity
Role in Longevity
Requirement in longevity paradigms in yeast, worms and flies. Overexpression of specific atg genes and protein levels found to promotes longevity in flies, mice, and humans
Reference
Reference
Mizushima (2011), Lapierre (2015)
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