Embedded Files
STAC-5
IUPAC Name: N-(1,3-thiazol-2-yl)-2-[2-(trifluoromethyl)phenyl]-3H-imidazo[4,5-c]pyridine-7-carboxamide
Chemical Formula: C17H10F3N5OS
Chemical Formula: C17H10F3N5OS
Exact Mass: 389.06 g/mol
Exact Mass: 389.06 g/mol
Molecular Weight: 389.4 g/mol
Molecular Weight: 389.4 g/mol
Elemental Analysis: C(52.44%) H(2.59%) F(14.64%) N(17.99%) O(4.11%) S(8.24%)
Elemental Analysis: C(52.44%) H(2.59%) F(14.64%) N(17.99%) O(4.11%) S(8.24%)
SMILES: C1=CC=C(C(=C1)C2=NC3=C(N2)C=NC=C3C(=O)NC4=NC=CS4)C(F)(F)F
SMILES: C1=CC=C(C(=C1)C2=NC3=C(N2)C=NC=C3C(=O)NC4=NC=CS4)C(F)(F)F
PubChem CID: 87307650
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
SIRT1
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Activator of Sirt1
Biological Activity
Biological Activity
Allosteric binding to SIRT1
Reference
Reference
Hubbard (2013), Sinclair (2014)
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