Embedded Files
ACMSD
Name
Name
Alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase
Relevant Pathway
Relevant Pathway
Function
Function
Decarboxylates intermediate tryptophan metabolite alpha-amino-beta-carboxy-muconate-semialdehyde (ACMS) to alpha-amino-muconate-semialdehyde (AMS), which spontaneously forms picolinic acid which is metabolised to acetyl-CoA
Role in Longevity
Role in Longevity
Key regulator of NAD+ metabolism
Regulation of niacin requirements
Reference
Reference
Palzer (2018)
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