Embedded Files
RAGE
Name
Name
Receptor for advanced glycation end-products
Relevant Pathway
Relevant Pathway
Function
Function
Ability to bind to advanced glycation end-products (AGEs), and numbers pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Interaction leads to pro-inflammatory response, can lead to stress involving mitochondrial dysfunction or cellular senesence
Role in Longevity
Role in Longevity
Key pattern recognition receptor for inflammaging
Reference
Reference
Teissier (2019)
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