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1-Methylnicotinamide
Chemical Formula: C7H9N2O+
Chemical Formula: C7H9N2O+
Exact Mass: 137.07 g/mol
Exact Mass: 137.07 g/mol
Molecular Weight: 137.16 g/mol
Molecular Weight: 137.16 g/mol
Elemental Analysis: C(61.30%) H(6.61%) N(20.42%) O(11.66%)
Elemental Analysis: C(61.30%) H(6.61%) N(20.42%) O(11.66%)
SMILES: C[N+]1=CC=CC(=C1)C(=O)N
SMILES: C[N+]1=CC=CC(=C1)C(=O)N
Chemical Structure:
Alternative Names
Alternative Names
MNA
Source
Source
Milk
Beer
Protein Target/Signalling
Protein Target/Signalling
Sirtuins
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in C. elegans
Biological Activity
Biological Activity
Metabolite of NAM, extends lifespan in C. elegans even in absence of sir-2.1, substrate for GAD-3 to generate hydrogen peroxide acting as mitohormetic ROS signal to promote longevity
Reference
Reference
Schmeisser (2013)
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