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HPK-1
Name
Name
Homeodomain-interacting protein kinase
Relevant Pathway
Relevant Pathway
Function
Function
C. elegans Hipk homolog
Essential cofactor of multiple transcriptional responses to preserve proteostasis
Role in Longevity
Role in Longevity
Preserves proteostasis and extends longevity through pathways defined by HSF-1 and mTORC1, via induction of autophagy in response to DR or inactivation of mTORC1
Reference
Reference
Das (2017)
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