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NRF2
Name
Name
Nuclear factor erythroid 2-related factor 2
Relevant Pathway
Relevant Pathway
Function
Function
Basic leucine zipper protein regulating antioxidant proteins, tumour suppressor gene
Keap1/Nrf2 signalling mediates cellular responses to oxidative stress
Role in Longevity
Role in Longevity
Regulates antioxidant and anti-inflammatory pathways, activity induced by caloric restriction
Reference
Reference
Martín-Montalvo (2010), Vomhof-DeKrey (2012), Loboda (2016), Sykiotis (2008)
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