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Icariin
Chemical Formula: C33H40O15
Chemical Formula: C33H40O15
Exact Mass: 676.24 g/mol
Exact Mass: 676.24 g/mol
Molecular Weight: 676.7 g/mol
Molecular Weight: 676.7 g/mol
Elemental Analysis: C(58.57%) H(5.96%) O(35.47%)
Elemental Analysis: C(58.57%) H(5.96%) O(35.47%)
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O
PubChem CID: 5318997
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Epimedium (horny goat weed)
Protein Target/Signalling
Protein Target/Signalling
Akt
PPAR
SIRT1
NF-kB
PDE5
Biological Pathway
Biological Pathway
mTOR
IGF/IIS
Epigenetic modification
Inflammation
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in mice
Mainly neuroprotective
Biological Activity
Biological Activity
Extends lifespan in mice
Enhanced motor recovery after spinal cord injury in mice through inhibition of pro-inflammatory factors, oxidative stress, and neuronal apoptosis via mitochondrial apoptotic pathways
Reference
Reference
Jin (2019), Zhang (2015), Li (2018e)
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