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Tenovin-6
Chemical Formula: C25H34N4O2S
Chemical Formula: C25H34N4O2S
Exact Mass: 454.24 g/mol
Exact Mass: 454.24 g/mol
Molecular Weight: 454.6 g/mol
Molecular Weight: 454.6 g/mol
Elemental Analysis: C(66.05%) H(7.54%) N(12.32%) O(7.04%) S(7.05%)
Elemental Analysis: C(66.05%) H(7.54%) N(12.32%) O(7.04%) S(7.05%)
SMILES: CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C
SMILES: CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C
PubChem CID: 24772043
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
SIRT1
SIRT2
p53
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Biological Activity
Biological Activity
Inhibition of both SIRT1 and SIRT2 in vitro, activation of p53 and inhibition of tumour growth in vivo
Reference
Reference
Lain (2008), Villalba (2012)
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