Embedded Files
PARP-1
Name
Name
Poly [ADP-ribose] polymerase 1
Relevant Pathway
Relevant Pathway
Function
Function
DNA repair, activated by DNA-strand breaks, regulating the accessibility of the DNA repair site to other repair enzymes. Binds to DNA strand and cleaves NAD+ into nicotinamide and ADP-ribose
Role in Longevity
Role in Longevity
PARP-1 and PARP-2 involved in telomere maintenance, correlation between poly(aDP-ribosyl)ation capacity and lifespan
Reference
Reference
Jubin (2016), Bürkle (2005), Southan (2003)
Page updated
Google Sites
Report abuse