Embedded Files
Adjudin
Chemical Formula: C15H12Cl2N4O
Chemical Formula: C15H12Cl2N4O
Exact Mass: 334.04 g/mol
Exact Mass: 334.04 g/mol
Molecular Weight: 335.2 g/mol
Molecular Weight: 335.2 g/mol
Elemental Analysis: C(53.75%) H(3.61%) Cl(21.15%) N(16.72%) O(4.77%)
Elemental Analysis: C(53.75%) H(3.61%) Cl(21.15%) N(16.72%) O(4.77%)
SMILES: C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)NN
SMILES: C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)NN
PubChem CID: 9819086
Chemical Structure:
Alternative Names
Alternative Names
AF-2364; 1-(2,4-dichlorobenzyl) 1H-indazole-3-carbo-hydrazide
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
SIRT3
FOXO3a
SOD2
Biological Pathway
Biological Pathway
Epigenetic modification
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Delayed cellular senesence
Biological Activity
Biological Activity
Upregulation of SIRT3, raising FOXO3a and SOD2 levels and reducing ROS production to delay hydroxyurea-induced senescence in mouse embryo fibroblasts
Reference
Reference
Geng (2018)
Page updated
Google Sites
Report abuse