Embedded Files
Nimbolide
Chemical Formula: C27H30O7
Chemical Formula: C27H30O7
Exact Mass: 466.20 g/mol
Exact Mass: 466.20 g/mol
Molecular Weight: 466.5 g/mol
Molecular Weight: 466.5 g/mol
Elemental Analysis: C(69.51%) H(6.48%) O(24.01%)
Elemental Analysis: C(69.51%) H(6.48%) O(24.01%)
SMILES: CC1=C2[C@@H](C[C@H]1C3=COC=C3)O[C@H]4[C@@]2([C@@H]([C@@]5([C@H]6[C@H]4OC(=O)[C@@]6(C=CC5=O)C)C)CC(=O)OC)C
SMILES: CC1=C2[C@@H](C[C@H]1C3=COC=C3)O[C@H]4[C@@]2([C@@H]([C@@]5([C@H]6[C@H]4OC(=O)[C@@]6(C=CC5=O)C)C)CC(=O)OC)C
PubChem CID: 12313376
Alternative Names
Alternative Names
Source
Source
Neem tree
Protein Target/Signalling
Protein Target/Signalling
PI3K/Akt/GSK-3β
Biological Pathway
Biological Pathway
mTOR
IGF/IIS
Telomeres
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Biological Activity
Biological Activity
Inhibition of cytoprotective autophagy to activate apoptosis through modulation of PI3K/Akt/GSK-3β signalling pathway in oral cancer in vitro and in vivo
Reference
Reference
Sophia (2018)
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