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Rapamycin
Chemical Formula: C51H79NO13
Chemical Formula: C51H79NO13
Exact Mass: 913.56 g/mol
Exact Mass: 913.56 g/mol
Molecular Weight: 914.2 g/mol
Molecular Weight: 914.2 g/mol
Elemental Analysis: C(67.01%) H(8.71%) N(1.53%) O(22.75%)
Elemental Analysis: C(67.01%) H(8.71%) N(1.53%) O(22.75%)
SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
PubChem CID: 5284616
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Drug
Protein Target/Signalling
Protein Target/Signalling
mTOR
Biological Pathway
Biological Pathway
mTOR
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Well known mTOR inhibitor. Promotes generation of induced pluripotent stem cells (iPSCs)
Biological Activity
Biological Activity
Well known mTOR inhibitor. Promotes generation of induced pluripotent stem cells (iPSCs)
Potent SASP suppressor
Reference
Reference
López-Otín (2013), Chen (2011), Herranz (2015)
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