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α-tocopherol
Chemical Formula: C29H50O2
Chemical Formula: C29H50O2
Exact Mass: 430.38 g/mol
Exact Mass: 430.38 g/mol
Molecular Weight: 430.7 g/mol
Molecular Weight: 430.7 g/mol
Elemental Analysis: C(80.87%) H(11.70%) O(7.43%)
Elemental Analysis: C(80.87%) H(11.70%) O(7.43%)
SMILES: CC1=C(C2=C(CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=C1O)C)C
SMILES: CC1=C(C2=C(CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=C1O)C)C
PubChem CID: 14985
Chemical Structure:
Alternative Names
Alternative Names
Source
Source
Plants
Animals
Protein Target/Signalling
Protein Target/Signalling
NF-κB
mTOR
P21
Biological Pathway
Biological Pathway
Inflammation
mTOR
Longevity-Related Effects/Anti-ageing mechanism
Longevity-Related Effects/Anti-ageing mechanism
Lifespan extension in mice
Suppression of SASP
Biological Activity
Biological Activity
Lifespan extension observed in mammals may reflect anticancer effect via induction of P21 signalling
Prevention and treatment of age-related pathologies such as cardiovascular and metabolic diseases, cancer, neurodegenerative diseases, and sarcopenia, mainly via inhibition of cellular senesence and inflammation
High intake reduces risk of type 2 diabetes in humans
Reference
Reference
Banks (2010), Malavolta (2018), Arnlov (2009)
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