Drake Stadium Des Moines, IA, April 23, 1921
The 4x440 yard relay at the Drake Relays was run at a slightly faster pace than at the Penn Relays a week later. In the university division, the University of Notre Dame team won the A-race with a time of 3:22.4. In the B-race, the University of Illinois quartet pulled ahead, churning out a winning time of 3:22.0. This was enough for a shared third place in the season's world rankings.