Artikel från Håkan Almkvist:
Association Between MRI Exposure During Pregnancy
and Fetal and Childhood Outcomes
Ray, JAMA. 2016;316(9):952-961. doi:10.1001/jama.2016.12126
Discussion
Within a large population of pregnant women who received
universal health care and whose pregnancies lasted a mini-
mum of 21 gestational weeks, 1 in 250 had an MRI in preg-
nancy, including 1 in 1200 in the first trimester and 1 in 3000
with gadolinium contrast. Maternal MRI in the first trimester
was not associated with a higher risk of stillbirth or neonatal
death, congenital anomalies, neoplasm, or hearing loss. The
risk of vision loss was only seen in a subgroup analysis of MRI
exposure at 5 to 10 weeks’ gestation. Exposure to gadolinium-
enhanced MRI at any gestation was not associated with a
greater risk of congenital anomalies. Although the NSF-like out-
come was extremely rare, gadolinium-enhanced MRI was as-
sociated with an adjusted HR of 1.36 for any rheumatological,
inflammatory or infiltrative skin condition up to age 4 years,
and an adjusted RR of 3.70 for stillbirth or neonatal death, al-
beit with just 7 events in the gadolinium MRI group.