SARS-CoV-2 RBD h-ACE2 Complex

SARS-CoV-2 RBD + ACE2 + B0AT1 (6M17) IMPORTANT!

Note: Chains B and D are ACE-2

Note: Chains E and F are 2019 n-CoV Receptor Binding Domain

Chains E and B interact with one another, and D and F interact with one another

Dr Norimatsu edited 6M17 and created a PDB file (Possible broken link) for viral RBD + soluble ACE2 (21-615).

Please use "select byres resi number around 6" in PyMOL to find residue interactions.

For example, "select byres resi 21 around 6".

table completed by EF, verified by AH

Based on Figure 2

Interaction is stronger between necks than PDs

In open state. PDs are no longer in contact

table completed by EF

Soluble ACE2 (1R42) IMPORTANT!

Note: does not include alpha helix H bonds; bonds from alpha helix residues to residues not in the alpha helix are included

table completed by EF