COVID-19 Project

Please keep this page as concise as possible (video).

The goal of this project is to design a high-affinity biologic for COVID-19. It will be analogous to antibodies that bind to SARS-Cov-2, the virus that causes COVID-19. SARS-CoV-2 is a single-stranded positive-sense RNA virus. It is an enveloped virus with a helical capsid, and requires membrane fusion for entry into a human cell (Millet and Whittaker, 2018). This is an attractive target for therapeutic interventions (Kruse, 2020). The project is divided into 3 stages.

We want to send our manuscript to Biochemistry for publication.

What you can do to help the team

1. Help us calculate side chain interaction energies. (Precise/Technical Learning Pattern)

2. Help us with writing of a manuscript by doing literature review. (Precise Learning Pattern)

3. Help us by designing a small decoy and creating the PDB file and alignment file for Modeller. (Technical Learning Pattern)

4. Help us run MD Simulations and analyze the trajectories.

Please check the current progress.