Alle dyr sover
I dypsøvn er sansene koblet ut, man er sårbar, og et lett bytte for rovdyr.
Alle dyr har to grunninstinkter: overlevelse og forplantning.
I dypsøvn er man både forsvarsløs og lite forplantningsdyktig…
Evolusjonsmessig må søvn ha en stor gevinst med henblikk på overlevelse og forplantning…‽
HVORFOR må man sove når det er så risikabelt?
Løsningen på søvnens mysterium kan ligge i glymfesystemet.
Man har lenge trodd at hjernen og sentralnervesystemet ikke omfattes av lymfesystemet, men nå hevder noen at hjernen har sitt lymfesystem, ofte kalt Glymfe (Glia Lymph)…
Glymfesystemet renser hjernen for slagg- og avfallsstoffer, og noen mener at søvnmangel kan bidra til Alzheimers sykdom og demens…‽
Hvorfor må man sove for å få fart på glymfesystemet?
Glymfe skal produseres og transporteres, og dette krever en betydelig energiomsetning.
Hjernens energiomsetning viser kun en liten reduksjon når man sover, selv om hjernen da ikke omsetter energi på å behandle sanseinntrykk eller på å dirigere motorikk.
Den ledige energiomsetningen utnyttes av glymfesystemet som da kan arbeide for fullt…‽
The Role of Sleep in Learning and Memory, Science, 2001-11-02 (JSTOR)
Clues to the functions of mammalian sleep, Nature, 2005-10-26 (PMC)
Maiken Nedergaard: Neuroscience. Garbage truck of the brain, Science, 2013-06-28, (PDF)
Emily Underwood: Sleep: The Ultimate Brainwasher?, Science, 2013-10-17
Sleep Drives Metabolite Clearance from the Adult Brain, Science, 2013-10-18 (PDF)
The Glymphatic System – A Beginner's Guide, Neurochemical Research, 2015-05-07 (PMC)
Goodnight. Sleep Clean, Sleep, 2016-04-03
Understanding the Glymphatic System, NeurOnline, 2018-07-17
The Cleansing Power of a Deep Night’s Sleep, UW Medicine, 2019-10-30
Sleeping Brain Waves Draw a Healthy Bath for Neurons, Quanta Magazine, 2019-12-16
The glymphatic hypothesis: the theory and the evidence, Fluids Barriers CNS , 2022-02-03
Sara Marie Ulv Larsen: Water channels in the brain can determine how deeply you sleep, Science Nordic, 2020-07-13
Lauren M. Hablitz and Maiken Nedergaard: The Glymphatic System: A Novel Component of Fundamental Neurobiology, Neuroscience, 2021-09-15
The Mind After Midnight: Nocturnal Wakefulness, Behavioral Dysregulation, and Psychopathology, Frontiers in Network Psychology, 2022-03-03
The Human Mind Is Not Meant to Be Awake After Midnight, Scientists Warn, ScienceAlert, 2022-08-04
A neuro-metabolic account of why daylong cognitive work alters the control of economic decisions, Current Biology, 2022-08-22
Pumpende blodårer vasker hjernen mens du sover, UiO, 2023-04-03
Flere lenker finnes i Sittesyken-Søvn og i Sittesyken-Glymfe-Glymph
“Even a soul submerged in sleep
is hard at work and helps
make something of the world.”
— Heraclitus (535-475BC)
“Sorrow can be alleviated by good sleep, a bath and a glass of wine”
― Thomas Aquinas (1225-1274)
“Early to bed and early to rise makes a man healthy, wealthy, and wise.”
— Benjamin Franklin (1706-1790)
“Think in the morning. Act in the noon. Eat in the evening. Sleep in the night.”
― William Blake (1757-1827)
“Think not, is my eleventh commandment; and sleep when you can, is my twelfth.”
― Herman Melville (1819-1891)
“The main facts in human life are five: birth, food, sleep, love and death.”
― E.M. Forster (1879-1970)
“Never waste any time you can spend sleeping.”
― Frank H. Knight (1885-1972)
“Happiness consists in getting enough sleep. Just that, nothing more.”
― Robert A. Heinlein (1907-1988)
"When action grows unprofitable, gather information; when information grows unprofitable, sleep."
― Ursula K. Le Guin (1929-2018)
“People also have a greater capacity when they aren’t worn down by work and worry. When people get enough sleep, they are more adept at difficult tasks, are more interpersonally sensitive, make better decisions, and are less likely to turn nasty.”
― Robert I. Sutton
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