TSS
Staphylococcal Toxic Shock Syndrome
Definition: Most often is associated with colonization of surgical wounds, burns, vagnitis, or tampon use in young women; cases are also seen after nasal packing for epistaxis.
Dx: fever, hypotension, mucosal hyperemia, macular desquamating erythroderma of the palms and soles, and multisystem involvement, such as vomiting, diarrhea, or multiorgan failure.
Definition: TSS is a life-threatening systemic disease caused by exotoxin super antigens produced by S. aureus or group A beta-hemolytic Streptococcus (GABHS) tissue infection.
Streptococcal Toxic Shock Syndrome
Associated with invasive GABHS infections, particularly necrotizing fasciitis or myositis (80% of cases)
Dx: sudden onset of severe diffuse or localized pain. Systemic manifestations are otherwise similar to Staph TSS, but the desquamating erythroderma is much less common.
Dxtic: BC are usually positive and ASO titers are elevated.
Mortality: higher than Staph TSS.
Dxtic testing:
Lab: BC are usually negative. CPK is elevated. Detection of TSST-1 in that is indicates protection against recurrence.
Mortality is relatively low.