Septic W/up in febrile infants

BC, CBC with diff, CSF (cc & diff, C&S, glu&protein); CXR, stool for C&S, focal leucocytes; UA, Urine C&S, HSV if mother is HSV positive.

Tx: Febrile infant inpatient. <29 days old.

Ampicillin + Cefotaxime or Gentamicin.

Febrile infant IP. >29 - <90 days old.

Ampicillin or Vanco (if MRSA) + Ceftriaxone

Febrile infant OP: Ceftriaxone IM, f/up 18 - 24 hrs later. Give 2nd dose of Ceftriaxone if needed.