MMSE

MMSE score = 24 - 30 normal.

• • MCI <24

  • Mild AD: 20-23

  • Moderate AD: 10-19

  • Severe AD: <10.

MMSE has strong education bias, and does not capture variability of "focal" syndromes of language d/o, visual-spatial-topographical impairment, or loss of executive function.

Not sensitive for mild dementia.

Orientation: Total 10 points.

• • What is the date today (ask general), then:

    • What year is it? (1)

    • What season is it? (1)

    • What month is it? (1)

    • What is the day of the week? (1)

    • What is the date today? (1)

  • Where are you questions:

    • What state are you in? (1)

    • What county are you in?(1)

    • What city are you in? (1)

    • Name this place (building or hosp). (1)

    • What floor are you on now? (1)

Registration: Total 3 points.

Name 3 objects (ball, flag, and tree) and have Pt. repeat them. Say about 1 word per sec. If Pt. misses object, ask Pt. to repeat them after you until he or she learns. Stop at 6 repeats.

Attention and Calculation: Total 5 points.

Substract 7s backwards from 100 in a serial fashion to 65. Alternatively, ask serial 3s from 20 or spell WORLD backwards.

Recall: Total 3 points

Do you recall the names of the three objects?

Language: Total 8 points

Ask Pt. to name a pencil and watch as you show these objects (2)

Repeat "No ifs, ands, or buts" (only one trial) (1)

3 step command. Give pt. a piece of plain blank paper and say, "Take the paper in your right hand (1), fold it in half (2), and put it on the floor (3)

Reading. Ask Pt. to read and perform task written on paper: "Close your eyes."(1)

Writing. Ask patient to write a sentence on a piece of paper (1)

Construction: Total 1 point

Ask patient to copy the design (interesecting pentagons. Substract 1 for fewer than tend angles or two interesecting lines.).